Electric Literature of 104-38-1, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.104-38-1, name is 1,4-Bis(2-hydroxyethoxy)benzene, molecular formula is C10H14O4, molecular weight is 198.2158, as common compound, the synthetic route is as follows.
Example 3 Synthesis of 2-[4-(2-hydroxyethoxy)cyclohexyloxy]ethanol (I-3) [0298] 2-[4-(2-hydroxyethoxy)phenoxy]ethanol are dissolved in 25.4 ml of 2-propanol. 1.2 g of 5% Pd/C catalyst (about 50% of water) are subsequently added. The hydrogenation is carried out using hydrogen 3.0 at 90-130 C. and 20 bar. When the hydrogenation is complete, the catalyst is separated off by filtration. The filtrate is freed from solvent in vacuo, giving 5.1 g of product in a mixture of cis and trans isomers.
Statistics shows that 104-38-1 is playing an increasingly important role. we look forward to future research findings about 1,4-Bis(2-hydroxyethoxy)benzene.
Reference:
Patent; Merck Patent GmbH; Rudolph, Thomas; Eisenberg, Sylvia; US2015/118165; (2015); A1;,
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