Kuribara, Takahito; Nakajima, Masaya; Nemoto, Tetsuhiro published the artcile< A visible-light activated secondary phosphine oxide ligand enabling Pd-catalyzed radical cross-couplings>, Application of C4H8O, the main research area is amine allyl methyl carbonate palladium photochem allylation; bromoalkane aryl alkene palladium photochem diastereoselective Heck reaction; aryl halide pyrrole palladium photochem radical cross coupling; haloarene palladium photochem dehalogenative hydrogenation.
A secondary phosphine oxide ligand bearing a visible-light sensitization moiety and apply it to Pd-catalyzed radical cross-coupling reactions was reported. The tautomeric phosphinous acid coordinates to palladium in-situ, allowing for pseudo-intramol. single-electron transfer between the ligand and palladium. Mol. design of the metal complexes aided by time-dependent d. functional theory calculations enables the involvement of allyl radicals from π-allyl palladium(II) complexes, and alkyl and aryl radicals from the corresponding halides and palladium(0) complex. This complex enables radical cross-couplings by ligand-to-Pd(II) and Pd(0)-to-ligand single-electron transfer under visible-light irradiation
Nature Communications published new progress about Allylation (photochem.). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Application of C4H8O.
Referemce:
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Alcohols – Chemistry LibreTexts