Reference of 6920-22-5, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 6920-22-5, name is Hexane-1,2-diol. A new synthetic method of this compound is introduced below.
General procedure: To an oven dried 9mL screw cap tube, a magnetic stir-bar, diamine (0.5mmol), vicinal diol (1.5mmol), CsOH.H2O (0.375mmol), Co-phen/C-800 (1.5mol%) and toluene (2.5mL) were added under argon atmosphere. Then, the tube was sealed and placed in a preheated oil bath at 150C for 24h. After completion of the reaction, the tube was allowed to cool at room temperature. Then, the solvent was evaporated under reduced pressure. Finally, the product was purified by silica gel column chromatography using ethyl acetate/hexane as eluent.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,6920-22-5, Hexane-1,2-diol, and friends who are interested can also refer to it.
Reference:
Article; Panja, Dibyajyoti; Paul, Bhaskar; Balasubramaniam, Bhuvaneshwari; Gupta, Raju K.; Kundu, Sabuj; Catalysis Communications; vol. 137; (2020);,
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