Choong, Ingrid C.; Serafimova, Iana; Fan, Junfa; Stockett, David; Chan, Erica; Cheeti, Sravanthi; Lu, Yafan; Fahr, Bruce; Pham, Phuongly; Arkin, Michelle R.; Walker, Duncan H.; Hoch, Ute published the artcile< A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties>, Synthetic Route of 6850-39-1, the main research area is diaminocyclohexyl analog SNS 032 preparation permeability bioavailability CDK inhibition.
The identification of a selective CDK2, 7, and 9 inhibitor (compound 4) with improved permeability is described. Compound 4 exhibits comparable CDK selectivity profile to SNS-032, but shows improved permeability and higher bioavailability in mice.
Bioorganic & Medicinal Chemistry Letters published new progress about Antitumor agents. 6850-39-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H13NO, Synthetic Route of 6850-39-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts