Sukuroglu, Ayca Aktas;Battal, Dilek;Kocadal, Kumsal;Sungur, Mehmet Ali;Cok, Ismet;Unlusayin, Irfan published 《Biomonitoring of bisphenol A, 4-nonylphenol, and 4-t-octylphenol in Turkish population: exposure and risk assessment》. The research results were published in《Environmental Science and Pollution Research》 in 2022.Category: alcohols-buliding-blocks The article conveys some information:
Biomonitoring studies are important tools to understand the effects of endocrine-disrupting compounds on human health. Up to now, there have been no biomonitoring and risk assessment studies conducted in Turkish population in which urinary bisphenol A (BPA), 4-nonylphenol (4-NP), and 4-t-octylphenol (4-t-OP) levels were measured simultaneously. The aim of this study is to measure urinary BPA, 4-NP, and 4-t-OP on Turkish population and conduct a risk assessment using urinary levels of chems. of interest. During the study, liquid chromatog. with tandem mass spectrometry (LC-MS/MS) was used to measure urinary levels of above-mentioned chems., and human biomonitoring was used as a risk assessment tool in 103 volunteers, living in Mersin Region, Turkey. Urinary BPA, 4-NP, and 4-t-OP were founded as 0.0079μg/g creatinine, 0.0177μg/g creatinine, and 0.0114μg/g creatinine, resp. The obtained estimated daily intakes (EDIs) were calculated as 0.095μg/kg bw/day, 0.041μg/kg bw/day, and 0.091μg/kg bw/day, for BPA, 4-NP, and 4-t-OP, resp. In conclusion, although no potential health risk due to BPA and 4-NP exposure was observed, there might be health risks associated with 4-t-OP exposure in the Turkish population.4-tert-Octylphenol (cas: 140-66-9) were involved in the experimental procedure.
4-tert-Octylphenol(cas: 140-66-9) has been used as a reference standard for the determination of the analyte in water samples using ultra-high-performance liquid chromatography/tandem mass spectrometry (UHPLC/MS/MS).Category: alcohols-buliding-blocks
Reference:
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