Category: alcohols-buliding-blocks《Development of β-cyclodextrin crosslinked citric acid encapsulated in polypropylene membrane protected-μ-solid-phase extraction device for enhancing the separation and preconcentration of endocrine disruptor compounds》 was published in 2022. The authors were Hafiz Rozaini, Muhammad Nur’;Saad, Bahruddin;Lim, Jun Wei;Yahaya, Noorfatimah;Ramachandran, Muggundha Raoov;Kiatkittipong, Worapon;Mohamad, Mardawani;Chan, Yi Jing;Goh, Pei Sean;Shaharun, Maizatul Shima, and the article was included in《Chemosphere》. The author mentioned the following in the article:
Endocrine disruptor compounds (EDCs) such as plasticisers, surfactants, pharmaceutical products, personal care products and pesticides are frequently released into the environmental waters. Therefore, a sensitive and environmentally friendly method is entailed to quantify these compounds at their trace level concentrations This study encapsulated the β-cyclodextrin crosslinked with citric acid in a polypropylene membrane protected-μ-solid phase extraction (BCD-CA μ-SPE) device for preconcg. the EDCs (triclosan, triclocarban, 2-phenylphenol, 4-tert-octylphenols and bisphenol A) in real water samples before the anal. by high-performance liquid chromatog. FT-IR and TGA results indicated that BCD-CA was successfully synthesized with the formation of ester linkage (1078.33 cm-1) and O-H stretching from carboxylic acid (3434.70 cm-1) with higher thermal stability as compared with native CD with the remaining weight above 72.1% at 500°C. Several critical parameters such as the sorbent loading, type and amount of salts, extraction time, sample volume, sample pH, type and volume of desorption solvents and desorption time were sequentially optimized and statistically validated. Under the optimum condition, the use of BCD-CA μ-SPE device had manifested good linearity (0.5-500μg L-1) with the determination of the coefficient range of 0.9807-0.9979. The p-values for the F-test and t-test (6.60 x 10-8 – 1.77 x 10-5) were lesser than 0.05 and low detection limits ranging from 0.27 to 0.84μg L-1 for all studied EDCs. The developed technique was also successfully applied for EDC analyses in four distinct real water samples, namely, wastewater, river water, tap water and mineral water, with good EDCs recoveries (80.2%-99.9%), low relative standard deviations (0.1%-3.8%, n = 3) with enrichment factor ranging from 9 to 82 folds. These results signified the potential of the BCD-CA μ-SPE device as an efficient, sensitive, and environmentally friendly approach for analyzing EDCs. And 4-tert-Octylphenol (cas: 140-66-9) was used in the research process.
4-tert-Octylphenol(cas: 140-66-9) is a common environmental pollutant showing weak estrogenic effects.Category: alcohols-buliding-blocks It has been shown to cause harm to vertebrate male reproductive systems.
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts