Doiuchi, Daiki;Uchida, Tatsuya published 《Catalytic Highly Regioselective C-H Oxygenation Using Water as the Oxygen Source: Preparation of 17O/18O-Isotope-Labeled Compounds》 in 2021. The article was appeared in 《Organic Letters》. They have made some progress in their research.Safety of 3,7-Dimethyloctan-3-ol The article mentions the following:
The oxygen atom of water was activated to iodosylbenzene derivatives via reversible hydrolysis of PhI(OOCR)2 and was used to the oxygen source for ruthenium(bpga)-catalyzed site-selective C-H oxygenation was reported. Ru(bpga)/PhI(OOCR)2/H2O system, sterically less bulky methinic and methylenic C-H bonds in various compounds was converted to desired oxygen functional groups in a site-selective manner. Using this method, oxygen-isotope labeled compounds such as D-[3-17O/18O]-mannose can be prepared in a multigram scale. To complete the study, the researchers used 3,7-Dimethyloctan-3-ol (cas: 78-69-3) .
3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Safety of 3,7-Dimethyloctan-3-ol Metabolite observed in cancer metabolism. It has a role as a human metabolite.
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts