Liu, E. published 《Design, synthesis and activities of novel tamibarotene analogues containing nitrogen heterocyclic ring》 in 2014. The article was appeared in 《Zhongguo Xinyao Zazhi》. They have made some progress in their research.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol The article mentions the following:
Three novel tamibarotene analogs containing nitrogen heterocyclic ring were designed, synthesized and evaluated. Target compounds were synthesized through 8 steps using 2,5-dimethyl-2,5-hexanediol and di-Et oxalate as starting materials. In vitro antitumor bioactivities against HL-60 cells and NB4 cells were evaluated by a MTT assay method. Their structures were identified by 1H-NMR, MS and elemental anal. Three compounds had inhibitory effects on HL-60 cells and NB4 cells. To complete the study, the researchers used 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) .
2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds.Recommanded Product: 2,5-Dimethyl-2,5-hexanediol
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