Adding a certain compound to certain chemical reactions, such as: 4170-90-5, Mesitylmethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 4170-90-5, blongs to alcohols-buliding-blocks compound. Safety of Mesitylmethanol
General procedure: To a mixture of 2 (0.10 mmol), catalyst 1 (5mol%), and alcohol 3 (0.11 mmol), was added CHCl3 (0.25 mL) at rt. The mixture was stirred at rt for indicated time in the tables and diluted with Et2O (5 mL). The organic layer was extracted with saturated aq. Na2CO3 (3 mL),and the aqueous layer was acidified with 6 N HCl. The aqueous layer was extracted with Et2O (5 mL), and the organic layer was dried over MgSO4 and concentrated in vacuo. The resulting residue was purified by column chromatography to afford the desired product 4.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,4170-90-5, its application will become more common.
Reference:
Article; Yamada, Ken-ichi; Oonishi, Akinori; Kuroda, Yusuke; Harada, Shingo; Kiyama, Hiroki; Yamaoka, Yousuke; Takasu, Kiyosei; Tetrahedron Letters; vol. 57; 36; (2016); p. 4098 – 4100;,
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