Category: alcohols-buliding-blocksIn 2013, Wei, Wei;Ma, Shuai;Han, Zeng-ying;Cao, Sheng-hua;Ding, Xiao-dong published 《Synthesis and optimization of bexarotene》. 《Huaxue Yanjiu Yu Yingyong》published the findings. The article contains the following contents:
The anti-cancer drug bexarotene was synthesized through seven main reactions such as chlorination, Friedel-Crafts alkylation, Friedel-Crafts acylation, Wittig reaction, hydrolysis reaction etc. This route was optimized greatly which featured with low cost and easy operation procedure. And 2,5-Dimethyl-2,5-hexanediol (cas: 110-03-2) was used in the research process.
2,5-Dimethyl-2,5-hexanediol(cas:110-03-2) was used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.Category: alcohols-buliding-blocks
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts