Recommanded Product: 4-tert-OctylphenolIn 2022, Jiang, Qunjiao;Liu, Runfeng;Liu, Tao;Liang, Jun;Wu, Yanan;Feng, Baoying;Liu, Shun;Li, Han;Pan, Dongxiang;Qiu, Xiaoqiang;Huang, Dongping published 《Relationship between exposure of alkylphenols in serum of pregnant women during early pregnancy and adverse birth outcomes》. 《Environmental Science and Pollution Research》published the findings. The article contains the following contents:
Alkylphenols are a type of endocrine disruptors, which are commonly found in personal care products, food, and water and are more harmful to the human body. To investigate the relationship between exposure of alkylphenols in serum of pregnant women during early pregnancy and adverse birth outcomes, a total of 2035 healthy pregnant women and their neonates were recruited in the birth cohort of Zhuang nationality in Guangxi from 2015 to 2018. The peripheral venous blood samples were collected from pregnant women in early pregnancy; the concentrations of nonylphenol (NP), 4-nonylphenol (4-N-NP), 4-tert-octylphenol (4-T-OP), and 4-n-octylphenol (4-N-OP) in serum were detected by ultra-performance liquid performance chromatog.-tandem mass spectrometry (UPLC-MS). Binary logistic regression showed that NP [OR = 1.40 (95% CI: 1.00, 1.94)] was pos. associated with preterm birth. Restricted cubic spline analyses showed that logNP and log4-T-OP had non-linearity associations with preterm birth (logNP: Poverall = 0.006, Pnon-linear = 0.003; log4-T-OP: Poverall = 0.004, Pnon-linear = 0.002). Multiple linear regression anal. showed that maternal serum concentration of NP was neg. associated with birth weight of perinatal infants (β = -14.68, 95% CI: -29.18, -0.19), which may be sensitive in male neonates (β = -26.18, 95% CI: -47.33, -5.02). The findings demonstrate that nonylphenol is a risk factor of preterm birth, and nonylphenol is neg. associated with the birth weight in male infants. The experimental procedure involved many compounds, such as 4-tert-Octylphenol (cas: 140-66-9) .
4-tert-Octylphenol(cas: 140-66-9) has been used as a reference standard for the determination of the analyte in water samples using ultra-high-performance liquid chromatography/tandem mass spectrometry (UHPLC/MS/MS).Recommanded Product: 4-tert-Octylphenol
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