Formula: C14H14O2In 2021, Jo, Junhyuk;Kim, Seonyul;Choi, Jun-Ho;Chung, Won-jin published 《A convenient pinacol coupling of diaryl ketones with B2pin2 via pyridine catalysis》. 《Chemical Communications (Cambridge, United Kingdom)》published the findings. The article contains the following contents:
A convenient, pyridine-boryl radical-mediated pinacol coupling of diaryl ketones is developed. In contrast to the conventional pinacol coupling that requires sensitive reducing metal, the current method employs a stable diboron reagent and pyridine Lewis base catalyst for the generation of a ketyl radical. The newly developed process is operationally simple, and the desired diols, e.g., I are produced with excellent efficiency in up to 99% yield within 1 h. The superior reactivity of diaryl ketone was observed over monoaryl carbonyl compounds and analyzed by DFT calculations, which suggests the necessity of both aromatic rings for the maximum stabilization of the transition states. The experimental procedure involved many compounds, such as rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .
rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Formula: C14H14O2) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.
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