Synthetic Route of 2043-47-2 ,Some common heterocyclic compound, 2043-47-2, molecular formula is C6H5F9O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Mixing 5.00 parts of the salt represented by the formula (I-1-c) and 25 parts of chloroform;Stirred at 23 C. for 30 minutes.In the mixture obtained,1.09 parts of a compound represented by the formula (I-1-d) is added,Furthermore, it stirred at 50 degreeC for 2 hours.After cooling the resulting reaction mixture to 23 C.2.67 parts of a compound represented by formula (I-1-e) are added,Furthermore, it stirred at 23 degreeC for 18 hours. After adding 50 parts of chloroform and 50 parts of ion-exchanged water to the obtained reaction mixture and stirring for 30 minutes at 23 C., the layers were separated to take out the organic layer.In the organic layer obtained,After adding 25 parts of a 5% aqueous solution of oxalic acid and stirring at 23 C. for 30 minutes,The layers were separated and the organic layer was taken out.After adding 25 parts of ion-exchanged water to the obtained organic layer and stirring at 23 C. for 30 minutes,Separated and took out the organic layer. This water washing operation was repeated 5 times.After filtering the obtained organic layer,The filtrate is concentrated to a concentrated residue,By adding 30 parts of tert-butyl methyl ether and stirring at 23 C. for 30 minutes, the supernatant is removed and concentrated by4.39 parts of a salt represented by the formula (I-1) were obtained.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 2043-47-2, 1H,1H,2H,2H-Nonafluoro-1-hexanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Sumitomo Chemical Co., Ltd.; Komuro, Katsuhiro; Takahashi, Yuki; Ichikawa, Koji; (96 pag.)JP2019/59712; (2019); A;,
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