In general, the hydroxyl group makes alcohols polar. 533-73-3, formula is C6H6O3, Because of hydrogen bonding, alcohols tend to have higher boiling points than comparable hydrocarbons and ethers. Category: alcohols-buliding-blocks
Arab, Yasmine;Zellagui, Amar;Ceylan, Ozgur;Olmez, Ozge Tokul;Duru, Mehmet Emin;Ozturk, Mehmet research published 《 In vitro antioxidant, antibiofilm, anticholinesterase and antityrosinase activities of Senecio hoggariensis hydro-methanolic extract》, the research content is summarized as follows. This study was carried out to identify the phenolic profile of hydro-methanolic extract from an endemic Algerian species Senecio hoggariensis and to investigate their health properties in particular with respect to antioxidant, anticholinesterase, anti-tyrosinase, antimicrobial and antibiofilm activities. Using high-performance liquid chromatog. (HPLC-DAD) techniques, nine compounds were identified: chlorogenic acid, curcumin, 4-hydroxylresorkinol, rutin, elagic acid, protocatechic acid, 4-hydroxy benzaldehid, pyrocatechol and 4-oh-benzoic acid. Antioxidant properties were determined using:DPPH• (2,2′-diphenyl-1-picrylhydrazyl radical), ABTS•+ (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radical cation)), β-carotene linolic acid, CUPRAC (cupric reducing antioxidant capacity) and metal chelating assays. The extract showed mild activity compared to standards The ability of the extract to inhibit enzymes: acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and tyrosinase was investigated. The studied extract showed relatively moderate tyrosinase inhibitory activity. Also, it inhibited the development of all tested microorganisms; the highest antibiofilm activity was 51.08% against Candida albicans ATCC 10239 biofilm production at 10 mg/mL concentration The findings indicate that S.hoggariensis may be an alternative source of content in the fight against bacterial infections.
533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., Category: alcohols-buliding-blocks
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts