Kamei, Yuji;Seino, Yusuke;Yamaguchi, Yuto;Yoshino, Tatsuhiko;Maeda, Satoshi;Kojima, Masahiro;Matsunaga, Shigeki published 《Silane- and peroxide-free hydrogen atom transfer hydrogenation using ascorbic acid and cobalt-photoredox dual catalysis》. The research results were published in《Nature Communications》 in 2021.Computed Properties of C10H22O The article conveys some information:
A silane- and peroxide-free HAT hydrogenation using a combined cobalt/photoredox catalysis and ascorbic acid (vitamin C) as a sole stoichiometric reactant was reported. A cobalt salophen complex is identified as the optimal cocatalyst for this environmentally benign HAT hydrogenation in aqueous media, which exhibits high functional-group tolerance. In addition to its applicability in the late-stage hydrogenation of amino-acid derivatives e.g., serine and drug mols., this method offers unique advantage in direct transformation of unprotected sugar derivatives e.g., (2R,3R,4R,5R,6S)-2-(hydroxymethyl)-6-(2-methylallyl)tetrahydro-2H-pyran-3,4,5-triol and allows the HAT hydrogenation of unprotected C-glycoside e.g., ((2R,3S,4R,5S)-3,4-dihydroxy-5-(2-methylallyl)tetrahydrofuran-2-yl)methyl acetate in higher yield compared to previously reported HAT hydrogenation protocols. The proposed mechanism is supported by exptl. and theor. studies. To complete the study, the researchers used 3,7-Dimethyloctan-3-ol (cas: 78-69-3) .
3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Computed Properties of C10H22O Metabolite observed in cancer metabolism. It has a role as a human metabolite.
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts