Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 24034-73-9, formula is C20H34O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Computed Properties of 24034-73-9
GC-MS analysis and antifungal activity of acetone extract of Conocephalum conicum (L) Underw (Liverwort) against aflatoxins producing fungi
Aflatoxins produced by Aspergillus are one of the extremely potent toxins of fungal origin that create serious health hazards in plants, animals and humans. The present study aims to search for a reliable and eco-friendly biocontrol of aspergillus by validating the use of some traditionally used bryophytes applying standard antifungal assays. Three bryophytes were collected from different altitudes (213-2100 m) of Western Himalaya. Crude organic extracts (methanol/ethanol or acetone) of three bryophytes viz. Conocephalum conicum (L.) Dumort., Marchantia papillata Raddi and Rhynchostegium vagans A. Jaeger were used for the control of Aspergillus flavus and A. parasiticus through food poisoned technique. The min. inhibitory concentration (MIC) and min. fungicidal concentration (MFC) was determined by micro broth dilution methods. Out of different crude organic extracts, acetone extract of Conocephalum conicum collected from Mukteshwar (altitude 2100 m) showed the highest percent inhibition (75±0.57-76±0.57%) with the lowest MFC (7.81μg/mL) against A. flavus and A. parasiticus which was compared with an antibiotic, fluconazole. The Gas Chromatog.-Mass Spectroscopy (GC-MS) anal. of the acetone extract of C. conicum revealed the presence of 30 major compounds out of which, riccardin C was found as a biomarker compound The scanning electron microscopic studies revealed the structural anomalies in the treated Aspergillus sp. which confirms the fungicidal potential of C. conicum against Aspergillus sp.
Computed Properties of 24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.
Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
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Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts