Extended knowledge of (2,3-Dimethoxyphenyl)methanol

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The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5653-67-8, name is (2,3-Dimethoxyphenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of (2,3-Dimethoxyphenyl)methanol

A. 2,3-Dimethoxybenzyl chloride Thionyl chloride (288 g) is added over 1.5 hour to a stirred solution of 2,3-dimethoxybenzyl alcohol (400 g) and 2,6-lutidine in methylene chloride (2 l). The reaction mixture is then stirred for 30 minutes after which it is washed with 2 N hydrochloric acid (7*1 l) and then with water. The organic layer is separated, dried (MgSO4) and evaporated to give a residue, which upon distillation yields 3,4-dimethoxybenzyl chloride (375 g), b.p. 145-150 C. at 20-25 nm (waterpump vacuum). The material solidifies on standing.

With the rapid development of chemical substances, we look forward to future research findings about 5653-67-8.

Reference:
Patent; Merrell-Toraude et Cie; US4342780; (1982); A;,
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Alcohols – Chemistry LibreTexts