Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 7661-33-8, is researched, Molecular C10H10ClNO, about Synthesis of haptens and potential radioligands and development of antibodies to insect growth regulators diflubenzuron and BAY SIR 8514, the main research direction is immunochem analysis diflubenzuron BAYSIR8514; hapten radioligand insect growth regulator.HPLC of Formula: 7661-33-8.
A variety of synthetic approaches were undertaken, leading to potential haptens and radioligands for the benzoylphenylurea insect growth regulators diflubenzuron [35367-38-5] and BAY SIR 8514 [64628-44-0]. One successful approach involved derivatization of the aniline N by Et 4-bromobutyrate followed by reaction with an appropriate isocyanate and cleavage of the Et ester to yield a free carboxypropyl “”handle””. Useful haptens were also synthesized by using a 3′-phenolic metabolite of diflubenzuron as well as acetate and amine functionalities in the 4′ position while the N-sulfenyl bond proved too unstable for use as an antigen. With the exception of the sulfenylated derivatives, the haptens lacked significant bol. activity on 3 insect species. Following protein coupling by the active ester or water-soluble diimide method, antibodies were raised to 2 diflubenzuron haptens in each of 7 rabbits immunized as demonstrated by radioimmunoassay using [14C]diflubenzuron, Ouchterlony gel diffusion, and immunoelectrophoresis.
In some applications, this compound(7661-33-8)HPLC of Formula: 7661-33-8 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
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