So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.de Almeida, Leonardo S.; de Mattos, Marcio C. S.; Esteves, Pierre M. researched the compound: 3-Bromo-4-chloronitrobenzene( cas:16588-26-4 ).SDS of cas: 16588-26-4.They published the article 《Tribromoisocyanuric acid in trifluoroacetic acid: an efficient system for smooth brominating of moderately deactivated arenes》 about this compound( cas:16588-26-4 ) in Synlett. Keywords: aryl bromide preparation; arene bromination tribromoisocyanuric acid. We’ll tell you more about this compound (cas:16588-26-4).
Moderately deactivated arenes are efficiently brominated by the reaction with tribromoisocyanuric acid (0.34 mol equiv) in trifluoroacetic acid at room temperature in 48-85% isolated yield. This medium avoids the polybromination of the substrate, observed in the same reaction performed in 98% H2SO4.
In addition to the literature in the link below, there is a lot of literature about this compound(3-Bromo-4-chloronitrobenzene)SDS of cas: 16588-26-4, illustrating the importance and wide applicability of this compound(16588-26-4).
Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts