So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Lv, Xin; Bao, Weiliang researched the compound: 1-(4-Chlorophenyl)pyrrolidin-2-one( cas:7661-33-8 ).Recommanded Product: 7661-33-8.They published the article 《A β-Keto Ester as a Novel, Efficient, and Versatile Ligand for Copper(I)-Catalyzed C-N, C-O, and C-S Coupling Reactions》 about this compound( cas:7661-33-8 ) in Journal of Organic Chemistry. Keywords: arylamide preparation copper catalyzed coupling keto ester ligand; arylimidazole preparation copper catalyzed coupling keto ester ligand; aryl ether preparation copper catalyzed coupling keto ester ligand; copper catalyzed coupling keto ester ligand aryl thioether preparation. We’ll tell you more about this compound (cas:7661-33-8).
Employing Et 2-oxocyclohexanecarboxylate as a novel, efficient, and versatile ligand, the copper-catalyzed coupling reactions of various N/O/S nucleophilic reagents with aryl halides could be successfully carried out under mild conditions. A variety of products including N-arylamides, N-arylimidazoles, aryl ethers, and aryl thioethers were synthesized in good to excellent yields.
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Reference:
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