Related Products of 73978-41-3 ,Some common heterocyclic compound, 73978-41-3, molecular formula is C7H9ClN6O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Initially, the compound 6-bromomethyl-pteridine-2,4-diamine as shown inFormula XIIIH9N N N(XIII)was prepared by first suspending 2,4-diamino-6-(hydroxymethyl)pteridine hydrochloride(2.29 g, 10 mmol) in 100 ml glacial acetic acid, warming to reflux and then allowing tocool to ambient temperature. Hydrobromic acid and 30% AcOH solution (191 ml) wasthen added and the flask stoppered for 4 days. The reaction mixture was then poured into1200 ml dry diethyl ether with stirring. The product was allowed to settle and excesssolvent was removed by decantation. The product was collected, washed with additionalether, and dried for later use.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,73978-41-3, its application will become more common.
Reference:
Patent; SERENEX, INC.; WO2006/14706; (2006); A2;,
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