Safety of 1-(4-Chlorophenyl)pyrrolidin-2-one. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 1-(4-Chlorophenyl)pyrrolidin-2-one, is researched, Molecular C10H10ClNO, CAS is 7661-33-8, about Selective cleavage and reconstruction of C-N/C-C bonds in saturated cyclic amines: tunable synthesis of lactams and functionalized acyclic amines. Author is He, Yan; Yang, Jintao; Zhang, Xinying; Fan, Xuesen.
Selective cleavage and functionalization of C-N/C-C bonds in saturated cyclic amines under the promotion of oxoammonium salt and tert-Bu hydroperoxide in the presence of different additives was developed. To be specific, cascade cleavage and reconstruction of C-N and C-C bonds took place under acidic conditions to provide pyrrolidin-2-ones. Under basic conditions, on the other hand, selective cleavage and functionalization of C-C bonds occurred to afford multi-functionalized acyclic N-formal amines. In addition, studies for revealing the intriguing reaction mechanisms was also been performed.
There is still a lot of research devoted to this compound(SMILES：O=C1N(C2=CC=C(Cl)C=C2)CCC1)Safety of 1-(4-Chlorophenyl)pyrrolidin-2-one, and with the development of science, more effects of this compound(7661-33-8) can be discovered.
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