The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Oxidation of organic compounds. XCIV. Synthesis of 3,5-dicyanopyridine by the oxidative ammonolysis of 3,5-butidine》. Authors are Suvorov, B. V.; Kagarlitskii, A. D.; Belova, N. A.; Kutzhanov, R. T..The article about the compound:Pyridine-3,5-dicarbonitrilecas:1195-58-0,SMILESS:N#CC1=CC(C#N)=CN=C1).Safety of Pyridine-3,5-dicarbonitrile. Through the article, more information about this compound (cas:1195-58-0) is conveyed.
Ammoxidation of 3,5-lutidine (I) using 1:9:17 I-O-NH3 at 350° in the presence of fused vanadium oxide-titanium oxide with a 0.5 sec contact time gave 40% 3,5-pyridinedicarbonitrile (II) and 5-methyl-3-pyridinecarbonitrile. Hydrolysis of II in aqueous NaOH gave 3,5-pyridinedicarboxylic acid.
There is still a lot of research devoted to this compound(SMILES：N#CC1=CC(C#N)=CN=C1)Safety of Pyridine-3,5-dicarbonitrile, and with the development of science, more effects of this compound(1195-58-0) can be discovered.
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