597-31-9, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal, molecular formula is C5H10O2, molecular weight is 102.1317, as common compound, the synthetic route is as follows.
The hydrogenation feed as described in example 1 was used.Catalyst UsedThe catalyst from example 1 was used.HydrogenationThe hydrogenation input was passed in the downflow mode at an H2 pressure of 37 bar through the reactor which was heated to 105 C. The WHSV was 0.32 kg of HPA/(kgcat*h). From 0 to 17% by weight (based on the hydrogenation feed) of a 50% strength by weight aqueous solution of trimethylamine were added to this mixture in order to set a pH of the hydrogenation output of greater than 8 (hydrogen/hydroxypivalaldehyde molar ratio: about 1.5). Part of the hydrogenation output was mixed back into the input (recycle mode). The ratio of recycle to input was 16:1. A mean conversion of 88.1% at a mean pH of 8.4 were achieved over a number of days.
Statistics shows that 597-31-9 is playing an increasingly important role. we look forward to future research findings about 3-Hydroxy-2,2-dimethylpropanal.
Reference:
Patent; BASF Aktiengesellschaft; US2007/282135; (2007); A1;,
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