Formula: C8H10O2. Authors Sato, K; Tanaka, S; Wang, JZ; Ishikawa, K; Tsuda, S; Narumi, T; Yoshiya, T; Mase, N in AMER CHEMICAL SOC published article about in [Sato, Kohei; Tanaka, Shoko] Shizuoka Univ, Grad Sch Sci & Technol, Hamamatsu, Shizuoka 4328561, Japan; [Wang, Junzhen; Ishikawa, Kenya] Shizuoka Univ, Dept Appl Chem & Biochem Engn, Fac Engn, Hamamatsu, Shizuoka 4328561, Japan; [Tsuda, Shugo; Yoshiya, Taku] Peptide Inst Inc, Ibaraki, Osaka 5670085, Japan; [Narumi, Tetsuo; Mase, Nobuyuki] Shizuoka Univ, Dept Appl Chem & Biochem Engn, Fac Engn,Grad Sch Sci & Technol, Course Appl Chem & Biochem Engn,Dept Engn,Grad Sc, Hamamatsu, Shizuoka 4328561, Japan; [Narumi, Tetsuo; Mase, Nobuyuki] Shizuoka Univ, Res Inst Green Sci & Technol, Hamamatsu, Shizuoka 4328561, Japan; [Sato, Kohei] Shizuoka Univ, Dept Appl Chem & Biochem Engn, Fac Engn, Course Appl Chem & Biochem Engn,Dept Engn,Grad Sc, Hamamatsu, Shizuoka 4328561, Japan in 2021, Cited 52. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5
A novel late-stage solubilization of peptides using hydrazides is described. A solubilizing tag was attached through a selective N-alkylation at a hydrazide moiety with the aid of a 2-picoline-borane complex in 50% acetic acid-hexafluoro-2-propanol. The tag, which tolerates ligation and desulfurization conditions, can be detached by a Cu-mediated selective oxidative hydrolysis of the N-alkyl hydrazide. This new method was validated through the synthesis of HIV-1 protease.
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