The origin of a common compound about 627-30-5

Statistics shows that 627-30-5 is playing an increasingly important role. we look forward to future research findings about 3-Chloropropan-1-ol.

627-30-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 627-30-5, name is 3-Chloropropan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

In a flask, 10.0 g (0.058 mol) of the compound represented by the formula (I-1a), 7.10 g (0.075 mol) of 3-chloropropanol, potassium carbonate 11.99 g (0.087 mol), and 100 mL of ethanol were added and heated under reflux for 5 days. After filtration, the solvent was distilled off and redissolved in toluene. After washing with brine, purification by column chromatography (silica gel) gave 10.7 g (0.046 mol) of the compound represented by the formula (I-11a).

Statistics shows that 627-30-5 is playing an increasingly important role. we look forward to future research findings about 3-Chloropropan-1-ol.

Reference:
Patent; DIC CORPORATION; HORIGUCHI, MASAHIRO; HAYASHI, MASANAO; KUSUMOTO, TETSUO; (90 pag.)JP6102423; (2017); B2;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts