623-04-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 623-04-1, name is (4-Aminophenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
Compound 6 was synthesized from the corresponding aminated compound. For this a solution of 4-aminobenzyl alcohol (2.15 g, 17.5 mmol) were dissolved in THF (25 mL) and dropped into a rounded bottom flask cooled at 4 oC containing an aqueous solution of H2SO4 (4.8 mL 98%, in 60 mL of water). -Caution for preparing the H2SO4 solution slowly add concentrated acid into cooled water and not vice versa – Over the obtained acid solution of 4 amino benzyl alcohol in ice bath, a solution of NaNO2 (1.45g, 21 mmol) dissolved in water (10 mL) was added. The mixture was led to react 1 h in ice bath. Passed that time NaN3 (1.8 g, 28.9 mmol) dissolved in 5 mL water was added to the solution. The mixture was led to react overnight. Passed that time 4-azidobenzyl alcohol was collected by three liquid-liquid extraction processes using dichloromethane (100 mL). Fractions were collected dried over anhydrous Na2SO4, concentrated and purified by flash column chromatography (DCM: MetOH 19:1). Yield 84%.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 623-04-1, (4-Aminophenyl)methanol.
Reference:
Article; Cao-Milan, Roberto; Castellanos, Laura; Gopalakrishnan, Sanjana; He, Luke D.; Huang, Rui; Landis, Ryan F.; Li, Cheng-Hsuan; Luther, David C.; Makabenta, Jessa Marie V.; Rotello, Vincent M.; Scaletti, Federica; Vachet, Richard W.; Wang, Li-Sheng; Zhang, Xianzhi; Chem; vol. 6; 5; (2020); p. 1113 – 1124;,
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