Recently I am researching about ONE-POT SYNTHESIS; SELECTIVE ALKYLATION; EFFICIENT; COMPLEX; ANILINES; SUBSTITUTION; OXIDATION; AMIDES, Saw an article supported by the NSFCNational Natural Science Foundation of China (NSFC) [22002023]. Name: (4-Methoxyphenyl)methanol. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Feng, XS; Huang, M. The CAS is 105-13-5. Through research, I have a further understanding and discovery of (4-Methoxyphenyl)methanol
A series of air-stable N-heterocyclic carbene (NHC) Ir(III) complexes (Ir1-6), bearing various combinations of chlorine, pyridine and NHC ligands, were assayed for the N-alkylation of amines with alcohols. It was found that Ir3, with two monodentate 1,3-bis-methyl-imidazolylidene (IMe) ligands, emerged as the most active complex. A large variety of amines and primary alcohols were efficiently converted into mono-N-alkylated amines in 53-96% yields. As a special highlight, for the challenging MeOH, selective N-monomethylation could be achieved using KOH as a base under an air atmosphere. Moreover, this catalytic system was successfully applied to the gram-scale synthesis of some valuable compounds. (C) 2021 Elsevier Ltd. All rights reserved.
Name: (4-Methoxyphenyl)methanol. About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Feng, XS; Huang, M or concate me.
Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts