Extended knowledge of (4-Methoxyphenyl)methanol

About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Donthireddy, SNR; Pandey, VK; Rit, A or concate me.. Quality Control of (4-Methoxyphenyl)methanol

I found the field of Chemistry very interesting. Saw the article [(PPh3)(2)NiCl2]-Catalyzed C-N Bond Formation Reaction via Borrowing Hydrogen Strategy: Access to Diverse Secondary Amines and Quinolines published in 2021. Quality Control of (4-Methoxyphenyl)methanol, Reprint Addresses Rit, A (corresponding author), Indian Inst Technol Madras, Dept Chem, Chennai 600036, Tamil Nadu, India.. The CAS is 105-13-5. Through research, I have a further understanding and discovery of (4-Methoxyphenyl)methanol

Commercially available [(PPh3)(2)NiCl2] was found to be an efficient catalyst for the mono-N-alkylation of (hetero)aromatic amines, employing alcohols to deliver diverse secondary amines, including the drug intermediates chloropyramine (5b) and mepyramine (5c), in excellent yields (up to 97%) via the borrowing hydrogen strategy. This method shows a superior activity (TON up to 10000) with a broad substrate scope at a low catalyst loading of 1 mol % and a short reaction time. Further, this strategy is also successful in accessing various quinoline derivatives following the acceptorless dehydrogenation pathway.

About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Donthireddy, SNR; Pandey, VK; Rit, A or concate me.. Quality Control of (4-Methoxyphenyl)methanol

Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts