An article Stereoselective 1,4-Addition of Primary Alcohols to gamma-Alkoxy-alpha,beta-unsaturated Esters WOS:000572131900002 published article about ASYMMETRIC CONJUGATE ADDITION; ENANTIOSELECTIVE SYNTHESIS; TETRAHYDROPYRAN; HYDRATION; ACIDS in [Inatomi, Saki; Takayanagi, Yuta; Watanabe, Kento; Toita, Akinori; Yamakoshi, Hiroyuki; Nakamura, Seiichi] Nagoya City Univ, Grad Sch Pharmaceut Sci, Mizuho Ku, 3-1 Tanabe Dori, Nagoya, Aichi 4678603, Japan in 2021, Cited 26. Formula: C8H10O2. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5
The scope and limitations of the diastereoselective 1,4-addition reaction of primary alcohols to gamma-alkoxy-alpha,beta-unsaturated esters were investigated. We found that a variety of sodium alkoxides, generated from the corresponding primary alcohols with NaH, underwent 1,4-addition reactions with (E)-enoates in CH(2)Cl(2)at -23 degrees C to give beta-alkoxy esters in modest yields with good to excellentsyn-selectivity, whereas stereoselectivity was not observed with the use of glycerol derivatives as nucleophiles. Cyclic acetal protection was found to play a pivotal role for the reaction to proceed.
About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Inatomi, S; Takayanagi, Y; Watanabe, K; Toita, A; Yamakoshi, H; Nakamura, S or concate me.. Formula: C8H10O2
Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts