Reference of 162358-05-6, Adding some certain compound to certain chemical reactions, such as: 162358-05-6, name is 2-(4-Octylphenyl)ethanol,molecular formula is C16H26O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 162358-05-6.
(1) 2-(4-Octylphenyl)ethyl iodide To a solution of 2-(4-octylphenyl)ethanol (25 g) in ether (200 ml)-acetonitrile (100 ml), imidazole (11 g) and triphenylphosphine (36 g) were added and the mixture was stirred at 0 C. for an hour. Iodine (38 g) was added to the solution and the whole mixture was stirred at 0 C. for 2 hours. Silica gel was added to the reaction solution and the mixture was filtered off. The precipitate was washed with a mixed solution of hexane-ethyl acetate (2:1). The filtrate and the solvent employed at washing were combined and concentrated. The residue was purified by silica gel chromatography (eluent; hexane-ethyl acetate=2:1) to give the subject compound (37 g). Rf value: 0.85 (hexane-ethyl acetate=4:1) MS: 344(M+) 1 H-NMR(400 MHz, CDCl3) delta: 0.88 (3H, t, J=8 Hz), 1.10-1.40 (10H, m), 1.50-1.65 (2H, m), 2.57 (2H, t, J=8 Hz), 3.14 (2H, t, J=8 Hz), 3.33 (2H, t, J=8 Hz), 7.09 (2H, d, J=8 Hz), 7.13 (2H, d, J=8 Hz)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 162358-05-6, 2-(4-Octylphenyl)ethanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Yoshitomi Pharmaceutical Industries, Ltd.; US5948820; (1999); A;,
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