Application of 39590-81-3, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 39590-81-3 as follows.
To a solution of (1-hydroxymethylcyclopropyl)methanol (1.02 g, 10 mmol) in DMF (20 mL),Add imidazole (1.36g, 20mmol) and cool to 0C.Add TBDPSCl (2.75 g, 10 mmol),The crude product was purified by column chromatography after 12 h of reaction to give compound 1-26 (2.046 g, yield 60%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,39590-81-3, its application will become more common.
Reference:
Patent; Sichuan Kelun Botai Bio-pharmaceutical Co., Ltd.; Liu Gang; Yu Hua; Dong Zhenwen; Du Jing; Wang Runjiang; Liu Wei; Zeng Hong; Song Hongmei; Ge Yong; Wang Lichun; Wang Jingyi; (44 pag.)CN107814798; (2018); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts