In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 629-41-4, name is 1,8-Octanediol, the common compound, a new synthetic route is introduced below. Computed Properties of C8H18O2
A new series of tris-malonate tethers that possess an open structure and bear alkyl groups as spacers were tested. The synthesis of one such tether that worked well with C60 is described in FIG. 6. PPTS: Pyridinium toluene-4-sulfonate. The intermediates of the synthesis of FIG. 6 were purified by flash column chromatography as follows, and were fully characterized by 13C-, 1H-NMR and mass spectrometry (FAB-MS). 1: SiO2, Hexane/EtOAc=1/1, Colorless oil. 2: SiO2, Hexane/EtOAc=7/3, Colorless oil. 3: SiO2, Hexane/EtOAc=3/2, Colorless oil. 4: SiO2, Hexane/EtOAc=1/1, Colorless oil. The yield of the first step of the synthesis was 39% because the bis-protected diol was also formed. The reason is that 1,8-octane-diol was not well soluble in CH2Cl2 and consequently, the mono-protected diol (soluble in CH2Cl2) was subjected to a rapid second reaction. We expect the use of larger amounts of solvent will improve the yield of the first step of the synthesis. Yields about 85% have been reported for similar diols according to the experimental procedure we followed. For details see: H. M. S. Kumar, B. V. S. Reddy, E. J. Reddy, J. S. Yadav, Chemistry Letters, 1999, 857-858.
The synthetic route of 629-41-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Hirsch, Andreas; Beuerle, Florian; Chronakis, Nikos; US2006/47167; (2006); A1;,
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