While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 6850-39-1, 3-Aminocyclohexanol.
Electric Literature of 6850-39-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6850-39-1, name is 3-Aminocyclohexanol. This compound has unique chemical properties. The synthetic route is as follows.
Example 79 : N-IS-rO-hydroxycyclohexyDaminoin^^ltriazolon^-alpyridin-l- yl} nicotinamide (79); 3-amino-cyclohexanol (Betapharma, 67.33 mg; 0.58 mmol; 2.0 eq.) was added to a mixture of N-(5-chloro[l,2,4]triazolo[l,5-a]pyridin-2-yl)nicotinamide ((B4), 80 mg; 0.29 mmol; 1.0 eq.), DIEA (76 mg; 0.58 mmol; 2.0 eq.) and activated Charcoal (8 mg) in tBuOH (0.8 mL). The reaction mixture was heated at 2000C for 2 x 30 min under microwave irradiation. After this time, it was filtered on a celite pad and the cake was washed with ACN. The filtrate was directly purified by RP-HPLC (Starting with 15% ACN in water for 5 min, then up to 30% in 10 min.). The title compound was isolated after lyophilisation as a white powder (51 mg, 49%). HPLC, Rt: 2.14 min. (purity 98.0%). LC/MS, M+(ESI): 353.0, M (ESI): 351.0.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 6850-39-1, 3-Aminocyclohexanol.
Reference:
Patent; LABORATOIRES SERONO SA; WO2009/27283; (2009); A1;,
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