Application of 5339-85-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5339-85-5, name is 2-(2-Aminophenyl)ethanol, molecular formula is C8H11NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: In a 25 mL Schlenk tube, ketones (1 mmol) and 2-aminobenzylalcohol (1.1 mmol) (for quinolines), or 2-(2-aminophenyl)ethanol(1 mmol) (for indole), [Cp*IrCl2]2 (1 mol %, 0.01 mmol, 7.96 mg), 4a(2 mol %, 0.02 mmol, 7.60 mg), KOH (10 mol %, 0.1 mmol, 5.6 mg),and toluene (5 mL) were placed under N2. The reaction mixturewasheated under reflux for 24 h. The reaction mixture was cooled toambient temperature, concentrated in vacuo, and purified by flashcolumn chromatography with petroleum ether/ethyl acetate toafford the corresponding quinolines and indole.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 5339-85-5, 2-(2-Aminophenyl)ethanol.
Reference:
Article; Huang, Shuang; Wu, Si-Peng; Zhou, Quan; Cui, He-Zhen; Hong, Xi; Lin, Yue-Jian; Hou, Xiu-Feng; Journal of Organometallic Chemistry; vol. 868; (2018); p. 14 – 23;,
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