Related Products of 623-04-1, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.623-04-1, name is (4-Aminophenyl)methanol, molecular formula is C7H9NO, molecular weight is 123.1525, as common compound, the synthetic route is as follows.
To a solution of N-ethoxycarbonyl-2-ethoxy-1,2- dihydroquinoline(EEDQ) (3.15 g, 2.59 mmol) and Fmoc-L-Leu (1, 4.15 g,2.35 mmol) in anhydrous DCM (250 mL) was added 4-aminobenzylalcohol (PAB-OH) (1.55 g, 2.59 mmol). The mixture was continuouslystirred at room temperature for 24 h. The solvent was thenevaporated under reduced pressure and the resulting residue waspurified by silica gel chromatography (DCM/MeOH 50 : 1 to 10 :1) to afford 2 (1.00 g, 73%) as a colorless powder. ESI-MS: m/z 459.2[MH], 481.2 [MNa], HPLC analysis (l 220 nm) > 95% of peakarea.
Statistics shows that 623-04-1 is playing an increasingly important role. we look forward to future research findings about (4-Aminophenyl)methanol.
Reference:
Article; Hao, Yun-Peng; Liu, Zheng-Yu; Ning, Jin-Feng; Sun, Xun; Tang, Mei-Lin; Zhou, Lu; European Journal of Medicinal Chemistry; vol. 193; (2020);,
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