In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 217479-60-2, name is 2,4,6-Trichlorobenzyl alcohol, the common compound, a new synthetic route is introduced below. Recommanded Product: 217479-60-2
a) Preparation of 1 ,3,5-trichloro-2-chloromethyl-benzene:To a stirred solution of 2,4,6-trichlorobenzylalcohol (10.0g; 47.3 mmoles) in chloroform (100ml) kept under nitrogen atmosphere, thionyl chloride (6.07ml_, 85.1 mmole) was added slowly at O0C over a period of 15 minutes followed by catalytic amount of DMF The reaction mix was allowed to stir at ambient temp for 3 hours. The reaction mixture was quenched with 5OmL of water; the aqueous layer was extracted with DCM (3 X 100ml). The combined organic layer was washed with 5% sodium bicarbonate solution (2 x 50ml) followed by brine (50ml) and dried over anhydrous sodium sulphate. The solvent was evaporated under reduced pressure. 10.9g (100.0% of theory) of 1 ,3,5-trichloro-2-chloromethyl-benzene was obtained in form of a white solid.1 HNMR (CDCI3, 400MHz): delta= 7.37 (2H, s); 4.82 (2H, s) Mass: M = 229.8
The synthetic route of 217479-60-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SYNGENTA PARTICIPATIONS AG; RAJAN, Ramya; WALTER, Harald; STIERLI, Daniel; WO2010/63700; (2010); A2;,
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