A new synthetic route of 110-73-6

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 110-73-6.

Adding some certain compound to certain chemical reactions, such as: 110-73-6, name is 2-(Ethylamino)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 110-73-6. 110-73-6

into a 500 ml four-necked flask, 26.7 parts of 2- (ethylamino) ethanol (Tokyo Chemical Industry Co., Ltd.) 133 parts of tetrahydrofuran, 1.8 parts of 4-dimethylaminopyridine (manufactured by Tokyo Chemical Industry Co., Ltd.) 33.4 parts of triethylamine and 65.5 parts of di-tert-butyl dicarbonate (manufactured by Tokyo Chemical Industry Co., Ltd.) And refluxed for 2 hours. After cooling the reaction solution to 40 C., Dichloromethane was added to the reaction solution, The organic layer was washed with water, Washed with saturated brine, and dried over anhydrous sodium sulfate. By concentrating the organic layer under reduced pressure, 51.1 parts of an intermediate represented by the following formula (109) was obtained.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 110-73-6.

Reference:
Patent; NIPPON KAYAKU COMPANY LIMITED; MIFUJI, AKIHIRO; OHTANI, KOHEI; KAMEYA, HIROSHI; (24 pag.)JP2017/114996; (2017); A;,
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