Extracurricular laboratory: Synthetic route of 1-(4-Biphenylyl)ethanol

The synthetic route of 3562-73-0 has been constantly updated, and we look forward to future research findings.

Adding a certain compound to certain chemical reactions, such as: 3562-73-0, 1-(4-Biphenylyl)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 3562-73-0, blongs to alcohols-buliding-blocks compound. SDS of cas: 3562-73-0

General procedure: Alcohol 3 (0.5 mmol) and NaBr(102.9 mg, 1 mmol) were dissolved in DMSO (1 mL), and then H2SO4 was added tothe solution under air at room temperature, and then the mixture were stirred at 60 Cfor 24 h. After cooling down to room temperature, the mixture were diluted withwater (10 mL) and extracted with EA (3 × 10 mL). The combined extracts werewashed with a saturated solution of NaCl (15 mL), dried over MgSO4, and evaporatedin vacuo. The residue was purified by chromatography on silica gel (petroleumether/ethyl acetate) to afford the bromohydrin 4.

The synthetic route of 3562-73-0 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Ai, Lingsheng; Wang, Weijin; Wei, Jialiang; Li, Qing; Song, Song; Jiao, Ning; Synlett; vol. 30; 4; (2019); p. 437 – 441;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts