Electric Literature of 104-38-1, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.104-38-1, name is 1,4-Bis(2-hydroxyethoxy)benzene, molecular formula is C10H14O4, molecular weight is 198.2158, as common compound, the synthetic route is as follows.
Example 120 2-[4-(2-{[3-(1-Piperazinyl)-2-pyrazinyl]oxy}ethoxy)phenoxy]ethanol, Maleate The title product was prepared from 1,4-bis(2-hydroxyethoxy)benzene. Yield of free base of the title compound 51%. The maleate salt was prepared: mp 127-129 C. MS m/z 361 (M+H). Anal. (C18H24N4O4.C4H4O4) C, H, N.
The chemical industry reduces the impact on the environment during synthesis 104-38-1, I believe this compound will play a more active role in future production and life.
Reference:
Patent; Biovitrum AB; US6465467; (2002); B1;,
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