In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4415-73-0, name is 1,1-Cyclobutanedimethanol, the common compound, a new synthetic route is introduced below. Formula: C6H12O2
B. Preparation of cis-1, 2-bis-(bromomethyl) cyclobutane (XXI) To 44 g of phosphorous tribromide (-10 C.) was added dropwise 10.7 g of distilled XX over a 1 hour period. The reaction mixture was warmed to 25 C. and stirred for 2 hours, then heated to 80-85 C. for 18 hours. The reaction mixture was cooled in ice and cold water added. The layers were separated and the aqueous layer was extracted with methylene chloride. The organic extracts were combined, washed with 5% aqueous sodium carbonate and water, then distilled to yield 13.8 g of the title compound XXI as a purple oil, bp 86 (vacuum pump): ir (CHCl3) 3.4, 7.0-8.1mu (no OH signal observed); nmr delta 1.3-2.5 (m, 4), 2.8 (m, 2), and 3.5 (m, 2).
The synthetic route of 4415-73-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Miles Laboratories, Inc.; US4206127; (1980); A;,
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