Electric Literature of 109240-30-4, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 109240-30-4, name is 1-(4-Bromophenyl)cyclopropanol. A new synthetic method of this compound is introduced below.
General procedure: An argon-degassed solution of cyclopropanol 1 (1 equiv) in t-BuOH (0.02 M) was added dropwise over 2 h to an argondegassed,stirred solution of 2-isocyano biphenyl 2 (2 equiv)and manganese(III) acetylacetonate (2.2 equiv) in t-BuOH(0.042 M) at 26 C. The resulting solution (0.01 M with respectto the cyclopropanol) was stirred for an additional 5 min beforethe solvent was removed under reduced pressure, and theresulting residue purified by flash chromatography to yield thedesired 2-substituted phenanthradine 3.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,109240-30-4, 1-(4-Bromophenyl)cyclopropanol, and friends who are interested can also refer to it.
Reference:
Article; Davis, Dexter C.; Haskins, Christopher W.; Dai, Mingji; Synlett; vol. 28; 8; (2017); p. 913 – 918;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts