Application of 33524-31-1 ,Some common heterocyclic compound, 33524-31-1, molecular formula is C9H12O3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: A mixture of the benzylic alcohol 1 (1 mmol) and 98% H2SO4 (1 mmol) in DMSO (3 mL) was stirred for the appropriate time under reflux conditions. The mixture was then cooled to r.t., and brine (4 mL) was added. The organic phase was extracted with CH2Cl2 (6 mL), and the organic layer was dried (Na2SO4), filtered, and concentrated under reduced pressure. In all cases, the reaction products were obtained with high purity, and did not require further purification by distillation or column chromatography.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,33524-31-1, its application will become more common.
Reference:
Article; Sheikhi, Ehsan; Adib, Mehdi; Karajabad, Morteza Akherati; Gohari, Seyed Jamal Addin; Synlett; vol. 29; 7; (2018); p. 974 – 978;,
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