The origin of a common compound about

Synthetic Route of 2240-88-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 2240-88-2, name is 3,3,3-Trifluoropropan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

Step 3; Preparation of tert-butyl 2-cvclopropyl-4-(3,3,3-trifluoropropoxy)-5,6,8,9- tetrahydro-7H-pyrimido[4,5-d]azepine-7-carboxylate; [057] 3,3,3-Trifluoropropan-1-ol (0.43 g, 3.7 mmol) was dissolved in 1 ,4-dioxane (5 mL). Potassium tert-butoxide (572 mg, 5.1 mmol) was added, and the mixture was stirred at rt for 15 min. tert-Butyl 4-chloro-2-cyclopropyl-5,6,8,9-tetrahydro-7H-pyrimido[4,5- EPO d]azepine-7-carboxylate (1.1 g, 3.4 mmol) was then added as a solution in 1 ,4-dioxane (5 ml_). The mixture was heated at 50°C overnight. The resulting white suspension was concentrated under reduced pressure, and the residue was partitioned between water and ethyl acetate. The organic layer was separated, dried (MgSO4), and concentrated under reduced pressure to give the title compound as a colorless oil (1.2 g, 94percent).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 2240-88-2, 3,3,3-Trifluoropropan-1-ol.

Reference:
Patent; BAYER PHARMACEUTICALS CORPORATION; WO2006/44762; (2006); A2;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts