The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 162358-05-6, name is 2-(4-Octylphenyl)ethanol. This compound has unique chemical properties. The synthetic route is as follows. Formula: C16H26O
General procedure: To a solution of 11 (400 mg, 1.71 mmol) and triethylamine (2 mL) in CH2Cl2 (10 mL) at 0 C was added methanesulfonyl chloride (0.66 mL, 8.53 mmol). After being stirred at room temperature for 6 h, the reaction mixture was evaporated, diluted with water, and the product was extracted with EtOAc. The extract was washed with brine, dried, and evaporated. To a solution of the reaction mixture (300 mg, 0.96 mmol) in DMF (10 mL) was added sodium azide (187 mg, 2.88 mmol). After the reaction mixture was heated at 80 C for 12 h, saturated aqueous ammonium chloride solution was added, and the mixture was extracted with EtOAc. The reaction mixture 15 (200 mg) was dissolved in EtOAc (10 mL), and 10% Pd/C (20 mg, 10 wt %) was added. After the reaction mixture was hydrogenated at room temperature for 12 h, the catalyst was removed by filtration through a pad of Celite, which was rinsed with EtOAc. Product 17 was obtained, without purification, as a colorless oil.
With the rapid development of chemical substances, we look forward to future research findings about 162358-05-6.
Reference:
Note; Oh, Yoon Sin; Lee, Taeho; Shin, Sang Mi; Shrestha, Jitendra; Lee, Doohyun; Park, Eun-Young; Baek, Dong Jae; Bulletin of the Korean Chemical Society; vol. 39; 2; (2018); p. 261 – 264;,
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