Synthetic Route of 15258-73-8 ,Some common heterocyclic compound, 15258-73-8, molecular formula is C7H6Cl2O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Compound 3-e (320 mg, 1.818 mmol) was obtained in an ice bath.Diisopropyl azodicarboxylate (400 mg, 2.00 mmol) was slowly added dropwise to a solution of 2-nitrophenol (250 mg, 1.818 mmol), triphenylphosphine (520 mg, 2.00 mmol) in tetrahydrofuran (5 mL). After stirring overnight at room temperature, the solvent was distilled off under reduced pressure, and the residue was purified by Prep-TLC (petroleum ether/ethyl acetate = 1:1) to give compound 3-d (0.30 g, 55%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,15258-73-8, its application will become more common.
Reference:
Patent; SHANGHAI KAIHUI TECHNOLOGY DEVELOPMENT CO;LTD; XU, ZUSHENG; Kaihui Science And Technology Development (Shanghai) Co., Ltd.; Xu Zusheng; (100 pag.)CN103304571; (2018); B;,
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