616-29-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 616-29-5, name is 1,3-Diaminopropan-2-ol. This compound has unique chemical properties. The synthetic route is as follows.
To a vigorously stirred ethanolic solution of salicylaldehyde (0.106 mL, 1 mmol) an ethanolic solution (20 mL) of 1,3-diamino-2-propanol (0.046 g, 0.5 mmol) was added dropwisely. The solution turned to light yellow and the mixture refluxed for 4 h. The resulting yellow powder was collected by filtration, washed with cold ethanol and ether and dried in the air ( Scheme 1 ). L2 was synthesized in order to compare with L1 from the point of view of the effect of substituent on DNA-binding measurements, cleavage activity, and cytotoxicity. Yield >70%; m.p. >250omicronC; F.W: 298.20, Color: yellow. Anal. calcd for C17H18N2O3: C, 68.44; H, 6.08; N,9.39%. Found: C, 68.04; H, 5.73, N, 9.56%. FT-IR (KBr, cm-1): 3394 (nuOH), 2893 (nuC-H), 1635 (nuC=N). UV-Vis (H2O): lambdamax (nm) = 386, 324. 1HNMR (250 MHz, DMSO-d6, room temperature): delta(ppm) = 13.52 (s, 2H, OH), 8.50 (s, 2H, HC=N), 7.42-6.85 (m, 8H, ArH), 5.17 (s, 1H, CHOH), 3.97 (s, 1H, CHOH), 3.76 (d, 2H, CH2), 3.57 (d, 2H, CH2).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 616-29-5, 1,3-Diaminopropan-2-ol.
Reference:
Article; Asadi, Zahra; Nasrollahi, Neda; Journal of Molecular Structure; vol. 1147; (2017); p. 582 – 593;,
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