Adding a certain compound to certain chemical reactions, such as: 3279-95-6, 2-(Aminooxy)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 3279-95-6, blongs to alcohols-buliding-blocks compound. Recommanded Product: 3279-95-6
The oxime compound, (E)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-[(2-hydroxy-ethoxyi mino)-methyl]-benzamide obtained in Step B of Example 6 may be easily prepared from 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-formyl-N-(2-hydroxy-ethoxy)-benzamide obtained in Step F of Example 1 by a reaction with 2-aminooxyethanol in THF at room temperature. Namely, 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-formyl-N-(2-hydroxy-ethoxy)-benzamide (1.37 g) and aminooxy ethanol (262 mg) were mixed in THF at room temperature for 12 hours, and then the solvent was evaporated to give 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-[(2-hydroxy-ethoxyimino)-methyl]-benzamide.
The synthetic route of 3279-95-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; CHUGAI SEIYAKU KABUSHIKI KAISHA; EP1780197; (2007); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts