Introduction of a new synthetic route about 2-(Aminooxy)ethanol

According to the analysis of related databases, 3279-95-6, the application of this compound in the production field has become more and more popular.

Electric Literature of 3279-95-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 3279-95-6, name is 2-(Aminooxy)ethanol, molecular formula is C2H7NO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Starting from intermediate 1.i (0.103 g; 0.2 mmol) and 2-aminooxyethanol (0.017 g; 0.221 mmol), the solutionwas stirred for th. The reaction mixture was directly purified by prep-HPLC (Method 1) to afford the titlecompound (0.084 g, 86% yield) as a white amorphous solid.MS1 (ESI, m/z): 485.1 [M+H*] for CigH2aN4O7So; tr = 0.65 min.

According to the analysis of related databases, 3279-95-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; IDORSIA PHARMACEUTICALS LTD; DIETHELM, Stefan; MATHIEU, Gaelle; PANCHAUD, Philippe; SURIVET, Jean-Philippe; TIDTEN-LUKSCH, Naomi; (123 pag.)WO2019/38362; (2019); A1;,
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