124-68-5, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 124-68-5, name is 2-Amino-2-methyl-1-propanol. A new synthetic method of this compound is introduced below.
2-Amino-2-methylpropan-l-ol (5g, 89.13 mmol) was reacted with benzyl chloroformate (8.61 g, 50.5 mmol), using triethylamine (7.38 g, 72.9 mmol) as base in DCM solvent (50mL) at room temperature for 3 hours. After completion of the reaction, the organic layer was washed with water (2 x 20 mL) and dried over sodium sulfate. The DCM layer upon concentration under vaccum afforded benzyl (l-hydroxy-2-methylpropan-2- yl)carbamate (Compound 7b).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 124-68-5, 2-Amino-2-methyl-1-propanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; NEKTAR THERAPEUTICS (INDIA) PVT. LTD.; NEKTAR THERAPEUTICS; SHARMA, PANKAJ; KHATRI, VIJAY KUMAR; GU, XUYUAN; SONG, YUAN; SHEN, MICHAEL LIXIN; SAUTHIER, JENNIFER RIGGS; ANAND, NEEL K.; KOZLOWSKI, ANTONI; ODINECS, ALEKSANDRS; RILEY, TIMOTHY A.; REN, ZHONGXU; MU. YONGQI; SHEN, XIAOMING; YUAN. XUEJUN; AURRECOECHEA, NATALIA; O’MAHONY, DONOGH JOHN ROGER; WO2015/92819; (2015); A2;,
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